Amikacin sulfate is broad spectrum aminoglycoside antibiotic derived from its counterpart kanamycin A. Amikacin sulfate (A003) contains a amikacin:sulfate ratio of 1:2.
TOKU-E offers three forms of amikacin: amikacin hydrate (A002), amikacin sulfate (1:2) (A003), and amikacin sulfate (1:1.8) (A070). All forms have similar potencies and are freely soluble in aqueous solution (50 mg/mL).
CAS Number
39831-55-5
Molecular Formula
C22H43N5O13 •2H2SO4
Molecular Weight
781.76
Mechanism of Action
Similar to other aminoglycosides, amikacin sulfate binds to the 30S ribosomal subunit resulting in an inability to read mRNA ultimately producing a faulty or nonexistent protein.
Storage Conditions
2-8°C
Tariff Code
2941.90.5000
Spectrum
Species susceptible to amikacin include gram negative bacteria such as Pseudomonas aeruginosa and several key enteric species. In addition, certain non-gram negative species including Mycobacterium tuberculosis have also demonstrated susceptibility to amikacin.