SKU: T117

size  
Quantity:
 
Price: make selection(s)
Description
Tedizolid is an oxazolidone antibiotic.  It is bacteriostatic against Gram-positive organisms.

    CAS Number

    856866-72-3

    Molecular Formula

    C17H15FN6O3

    Molecular Weight

    370.34 g/mol

    Mechanism of Action

    Tedizolid binds to the 23S rRNA of the 50S ribosomal subunit, preventing the formation of the 70S initiation complex and inhibiting protein synthesis.

    Storage Conditions

    2-8C

    Spectrum

    Effective against Gram-positive bacteria including MRSA and VRE, and linezolid-resistant strains

Specifications

    Form

    Powder

    Appearance

    White to off-white

    Source

    Synthetic

References

    References

    Choi S, Im W, and Bartizal K (2012) Activity of tedizolid phosphate (TR-701) in murine models of infection with penicillin-resistant and penicillin-sensitive Streptococcus pneumoniae. Antimicrob Agents Chemother. 2012 Sep;56(9):4713-7 PMID 22713339 Kisgen JJ, Mansour H, Unger NR, Childs LM (2014) Tedizolid: a new oxazolidinone antimicrobial. Am. J. Health Syst. Pharm. 71(8):621-33 PMID 24688035 Rybak JM, Marx K, Martin CA (2014) Early experience with tedizolid: Clinical efficacy, pharmacodynamics, and resistance. Pharmacother. 34(11):1198-208 PMID 25266820

Other Items In This Category