SKU: D030

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De-Plasma™ II is a potent and safe anti-Mycoplasma reagent which can be used to eliminate Mycoplasma contamination or can be used prophylactically to prevent contamination.  It consists of a proprietary mixture of five antimicrobial compounds with three separate anti-Mycoplasma targets.  It is non-toxic to most cell lines with an ED50 ten times larger than the treatment concentration. 

Mycoplasma belong to a unique genus of bacteria that lack cell walls.  Their small size and ubiquitous distribution account for their ability to go undetected in seemingly sterile cell cultures, but ultimately cause alterations in cell characteristics and processes, leading to inaccurate experimental conclusions.

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References

    References

    Drexler, HG (2002)  Mycoplasma contamination of cell cultures: Incidence, sources, effects, detection, elimination, prevention. Cytotechnol. 39(2):75-90

    Van Kuppeveld, FJM (1994)  Detection of Mycoplasma contamination in cell cultures by a Mycoplasma group-specific PCR." Appl. Environ. Microbiol. 60(1): 149-152

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