SKU: P092  / 
    CAS Number: 135575-42-7

    Pneumocandin B0

    $239.50 - $837.50
    Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from some species of Cryptosporiopsis, Glarea and Pezicula.

    Pneumocandin B0 is soluble in ethanol, methanol, DMF and DMSO.
    Mechanism of ActionPneumocandin B0 is a potent antifungal and acts by inhibiting the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.
    Molecular FormulaC50H80N8O17
    References671,329, a new antifungal agent I. Fermentation and isolation. Schwartz R. E. et al. J Antibiot. 1989, 42, 163.

    671,329, a new antifungal agent II. Structure determination Wichmann C. F. et al. J Antibiot. 1989, 42, 168.

    L-671,329, a new antifungal agent. III. In vitro activity, toxicity and efficacy in comparison to aculeacin. Fromtling R. A. & Abruzzo G. K. J. Antibiot. 1989, 42, 168.