Enopeptin A is an unusual depsipeptide featuring a pentaenone side chain, reported as an antiviral by researchers at RIKEN in 1991. Enopeptin A has potent antibacterial activity against Gram-positive and Gram-negative bacteria, including MRSA. Enopeptin A is the most non-polar of the acyldepsipeptide (ADEP) antibiotics which include the recently rediscovered compounds, A54556 A and B.
Enopeptin A is soluble in ethanol, methanol, DMF or DMSO.
|Mechanism of Action||Like other acyldepsipeptide (ADEP) antibiotics, Enopeptin A acts by activating and disregulating Clp-family proteins.|
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