SKU: C149  / 
    CAS Number: 868540-17-4

    Carfilzomib

    ₹17,410.62 - ₹67,925.94
    Carfilzomib is an anti-cancer tetrapeptide epoxyketone drug and is used for the treatment of multiple myeloma.
    Mechanism of ActionCarfilzomib prevents tumor growth by inhibiting 20S proteasome activity which leads to an accumulation of polyubiquinated proteins, and ultimately, cell cycle arrest or apoptosis.
    Molecular FormulaC40H57N5O7
    ReferencesPautasso, Chiara, Sara Bringhen, Chiara Cerrato, Valeria Magarotto, and Antonio Palumbo. "The Mechanism of Action, Pharmacokinetics, and Clinical Efficacy of Carfilzomib for the Treatment of Multiple Myeloma." Expert Opinion on Drug Metabolism & Toxicology 9.10 (2013): 1371-379.

    Kortuem, K. M., and A. K. Stewart. "Carfilzomib." Blood 121.6 (2013): 893-97.