SKU: A114  / 
    CAS Number: 88378-59-0

    Actinopyrone A

    $266.16 - $931.59
    Actinopyrone A is a gamma-pyrone compound isolated from a Streptomyces sp.. It shows selective (>10E6 fold) and potent (MIC 0.0001 µg/ml) activity against Helicobacter pylori, the principal cause of peptic ulcer disease. Actinopyrone A was originally identified for its coronary vasodilating activity and weak activity against some Gram positive bacteria and dermatophytes.

    Actinopyrone A is soluble in ethanol, methanol, DMF and DMSO.
    ReferencesGamma-Pyrone compounds with selective and potent anti-Helicobacter pylori activity. Taniguchi M., et al. , J. Antibiotics, 2000, 53, 844. 

    Actinopyrones A, B and C, new physiologically active substances. I. Producing organism, fermentation, isolation and biological properties. Yano K., et al. , J. Antibiotics, 1986, 39, 32. 

    Actinopyrones A, B and C, new physiologically active substances. II. Physico-chemical properties and chemical structures. Yano K., et al. , J. Antibiotics, 1986, 39, 38.