• Voriconazole

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SKU: V009

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Description
Voriconazole is an antifungal azole drug used in the treatment of a broad spectrum of yeasts and molds. Voriconazole is active against all Candida species and many Aspergillus species.

    CAS Number

    137234-62-9

    Molecular Formula

    C16H14F3N5O

    Molecular Weight

    349.31

    Mechanism of Action

    The mechanism of action of the azole family is to inhibit cytochrome P450, which is vital to membrane ergosterol function. The inhibition of ergosterol synthesis increases cell permeability which disrupts normal cellular function.

References

    References

    Johnson, L. B., & Kauffman, C. A. (2003). Voriconazole: A New Triazole Antifungal Agent. Clinical Infectious Diseases CLIN INFECT DIS, 36(5), 630-637. doi:10.1086/367933

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