• Virginiamycin S1, EvoPure� packaged and labeled in glass vial.

click on thumbnail to zoom
SKU: V014

Size  
Quantity:
  Click 'Bulk Order' for 10 or more
Price: make selection(s)
Description
Virginiamycin S1 is one of a family of depsipeptide antibiotics co-produced with ostreogrycin A and used as a synergistic mixture. Virginiamycin S1, also known as Staphylomycin S and Factor S among other synonyms, was discovered independently and named by several groups, leading to considerable confusion in the literature. Virginiamycin S1 differs from virginiamycin B in lacking the dimethylamino moiety on the phenyl ring.

Virginiamycin S1 is soluble in ethanol, methanol, DMF and DMSO.

    CAS Number

    23152-29-6

    Molecular Formula

    C43H49N7O10

    Molecular Weight

    823.9

    Mechanism of Action

    Virginiamycin S1 acts a synergist, binding to the conformational change of the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    The structures of the minor components of virginiamycin S. Vanderhaeghe, H. et al. , Tet. Lett. 1971, 2687.

    Virginiamycin: nomenclature. Crooy P. and De Neys R. J. Antibiot. 1972, 25, 371.

    A new species of Streptomyces producing virginiamycin family antibiotics. Ogata, K. et al. , J. Antibiot. 1978, 31, 1313.

Other Items In This Category