• Virginiamycin B, EvoPure� packaged and labeled in glass vial.

click on thumbnail to zoom
SKU: V021

Size  
Quantity:
  Click 'Bulk Order' for 10 or more
Price: make selection(s)
Description
Virginiamycin B is a depsipeptide antibiotic co-produced with ostreogrycin A, together used as a synergistic mixture. Virginiamycin B, also known as ostreogrycin B and streptogramin B among other synonyms, was discovered independently and named by several groups, leading to considerable confusion in the literature.

Virginiamycin B is soluble in ethanol, methanol, DMF and DMSO.

    CAS Number

    3131-03-1

    Molecular Formula

    C45H54N8O10

    Molecular Weight

    867.0

    Mechanism of Action

    Virginiamycin B acts a synergist, binding to the conformational change of the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    Preparation and properties of an antibiotic complex E129. Ball S. Biochem. J. 1958, 68, 24P.

    Inhibition of protein synthesis by streptogramins and related antibiotics. Cocito C. et al. J. Antimicrob. Chemotherap. 1997, 39, 7.

    Sites of interaction of streptogramin A and B antibiotics in the peptidyl transferase loop of 23 S rRNA and the synergism of their inhibitory mechanisms. Porse B. T. and Garrett R. A. J. Mol. Biol. 1999, 286, 375.

Other Items In This Category