• Tyrothricin packaged and labeled.

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SKU: T043

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Description

Tyrothricin is a large cyclic polypeptide antibiotic isolated from Brevibacillus brevis. Tyrothricin is composed of a mixture of tyrocidins and gramicidins which have antimicrobial activity against Gram-positive bacteria.

    CAS Number

    1404-88-2

    Molecular Formula

    C65H85N11O13

    Molecular Weight

    1228.44

    Mechanism of Action

    Tyrothricin targets and inserts into the gram positive membrane where it disrupts normal permeability leading to cell death. Tyrothricin is typically used topically as it would be too toxic to use systemically.

    Storage Conditions

    2-8°C

    Tariff Code

    2941.90.1050

    Spectrum

    Tyrothricin is effective against Gram positive bacteria and shows little to no effect against Gram negative bacteria.

Specifications

    Form

    Powder

    Appearance

    White or almost white powder

    Assay

    (As Is): ≥900µg/mg

References

    References

    Farmer, S. W., and et al. "Gramicidin S Is Active against Both Gram-positive and Gram-negative Bacteria." International Journal of Peptide and Protein Research 47.6 (1996): 460-66. www.ncbi.gov. Web. 4 Sept. 2012.

    "Tyrothricin." Http://lib.njutcm.edu.cn/. N.p., n.d. Web. 25 Mar. 2014.

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