• Tulathromycin A

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SKU: T107

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Tulathromycin is a semi-synthetic erythromycin belonging to the ring expanded aza-erythromycins. Ring expansion improves the acid lability compared with the parent erythromycins. Tulathromycin is regarded as the first of the triamilides, having a third amino (propylaminomethylene) group on a sugar to improve absorption. This modification provides a mixture of the two tulathromycin isomers (90:10) present in the commercial animal health product. Tulathromycin A represents the major component at 90% of the content.

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    Synthesis and activity of a novel class of tribasic macrocyclic antibiotics: The triamilides. Letavic M.A. et al. Bioorg. Med. Chem. Lett. 2002, 12, 2771.

    An analytical method for the analysis of tulathromycin, an equilibrating triamilide, in bovine and porcine plasma and lung. Gáler D. et al. J. Agric. Food Chem. 2004, 52, 2179.

    Tulathromycin: An overview of a new triamilide antimicrobial for livestock respiratory disease. Evans N.A. Vet. Therapeutics 2005, 6, 83.

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