• Tildipirosin packaged and labeled in glass vial.

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SKU: T092

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Description
Tildiprosin is a semi-synthetic antibiotic derived from a tylosin derivative by iodination and reaction with piperidine. The introduction of a third basic moiety into the tylosin core provides a wider spectrum of antibiotic action than the dibasic analogues such as tilmicosin, in particular good protection against Pasteurella in livestock. Tildipirosin's interaction with the ribosomal site of action differs from that of tylosin and tilmicosin.

Tildiprosin is soluble in ethanol, methanol, DMF and DMSO. 

    CAS Number

    328898-40-4

    Molecular Formula

    C41H71N3O8

    Molecular Weight

    734.0

    Storage Conditions

    Ambient < 30°C

Specifications

    Appearance

    White solid

References

    References

    Macrolide antibiotics and treatment and prophylaxis of Pasteurellosis using the same. Miyake et al. US Patent 6514946 2003. 

    Visualizing the 16-membered ring macrolides, tildipirosin and tilmicosin, bound to their ribosomal site. Poehlsgaard J. et al. ACS Chem. Biol. 2012, 7, 1351.

    Inhibition of protein synthesis on the ribosome by tildipirosin compared with other veterinary macrolides. Andersen N.M. et al. Antimicrob. Agents Chemother. 2012, 56, 6033.

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