• Thiocillin I packaged and labeled in glass vial.

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SKU: T090

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Description
Thiocillin I is the simplest of the macrocyclic thiazole peptides, first isolated from Bacillus badius. The final structural assignment and total synthesis of thiocillin I was only completed in 2011. Thiocillin I was originally reported as a potent antibacterial but its biological activity has not been extensively investigated.

Thiocillin I is soluble in ethanol, methanol, DMF and DMSO. 

    CAS Number

    59979-01-0

    Molecular Formula

    C48H49N13O10S6

    Molecular Weight

    1160.4

    Storage Conditions

    -20°C

Specifications

    Appearance

    White to light tan solid

References

    References

    Isolation of three new antibiotics, thiocillin I, II and III, related to Micrococcin P. (Studies on antibiotics from the genus Bacillus VIII). Shoji J. et al. J. Antibiot. 1976, 29, 366.

    Structural studies on thiocillins I, II and III (Studies on antibiotics from the genus Bacillus XXIX). Shoji J. et al. J. Antibiot. 1981, 34, 1126.

    Total synthesis and complete structural assignment of Thiocillin I. Aulakh S. & Ciufolini M.A. J. Am. Chem. Soc. 2011, 133, 5900.

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