• Thalidomide

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SKU: T113

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Description
Thalidomide is an antimalignancy cancer drug that has shown antiangiogenic and immunomodulatory activities.

This product is considered a dangerous good. Quantities above 1 g may be subject to additional shipping fees. Please contact us for specific questions.

    CAS Number

    50-35-1

    Molecular Formula

    C13H10N2O4

    Molecular Weight

    258.23

    Mechanism of Action

    The exact mechanism of thalidomide is unknown, however it has been shown to inhibit TNF-α, IL-6, IL-10 and IL-12 production while enhancing the production of IL-2, IL-4 and IL-5. It also effects natural killer cell toxicity and stimulates T lymphocytes.

    Storage Conditions

    <30°C

References

    References

    Singhal, S., & Mehta, J. (2001). Thalidomide in Cancer. Biodrugs, 15(3), 163-172. http://dx.doi.org/10.1016/S0753-3322(01)00146-9

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