• Ternatin

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Description
Ternatin is a cyclic peptide antifungal metabolite, first isolated from the fungus Didymocladium ternatum in Russia in 1974. More recently, ternatin has been demonstrated to be a potent inhibitor of fat accumulation in 3T3-L1 murine adipocytes. Note that this metabolite should not be confused with the plant flavonoid of the same name.

Ternatin is soluble in ethanol, methanol, DMF and DMSO and has limited water solubility. 

    CAS Number

    148619-41-4

    Molecular Formula

    C37H67N7O8

    Molecular Weight

    738.0

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    Convergent synthesis and in vivo inhibitory effect on fat accumulation of (−)-ternatin, a highly N-methylated cyclic peptide. Shimokawa K. et al. Bioorg. Med. Chem. Lett. 2005, 17, 4447.

    (−)-Ternatin, a highly N-methylated cyclic heptapeptide that inhibits fat accumulation: Structure and synthesis. Shimokawa K. et al. Tet. Lett. 2006, 47, 4445.

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