• Sitafloxacin sesquihydrate

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SKU: S107

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Description
Sitafloxacin sesquihydrate is a broad-spectrum fluoroquinoline antibiotic that is particularly active against gram-positive bacteria such as a pneumococci.

    CAS Number

    163253-35-8

    Molecular Formula

    C19H18ClF2N3O3•  1.5H2O

    Molecular Weight

    436.84

    Mechanism of Action

    Sitafloxacin has been shown to have a dual targeted mechanism of action. Other antibacterial quinolones target DNA gyrase or topoisomerase IV, but sitafloxacin targets both at a very similar rate. This double-target approach lowers the possibility of resistant strains.

    Storage Conditions

    -20┬░C

References

    References

    Onodera, Y., Uchida, Y., Tanaka, M., & Sato, K. (1999). Dual inhibitory activity of sitafloxacin (DU-6859a) against DNA gyrase and topoisomeraseIV of Streptococcus pneumoniae. Journal Of Antimicrobial Chemotherapy, 44(4), 533-536. http://dx.doi.org/10.1093/jac/44.4.533

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