Selective Agents

Several different types of antibiotics serve as selective agents in selective culture media to effectively isolate, or select for, a pathogenic microogranism from food, clinical, and environmental samples. Many times, these samples may contain a pathogenic microorganism among numerous types of relatively harmless bacteria and fungi. In order to effectively isolate the pathogenic organism, antibiotic selective agents are added to culture media to hinder growth of the harmless bacteria and fungi to ensure a non-competitive environment for the pathogenic organism.

An effective selective agent should not kill, or hinder the growth of the isolated pathogen. Theoretically, any antibiotic that doesn't target the selected pathogen but kills "background" growth of harmless microorganisms would be an ideal choice for use as a selective agent. The antimicrobials listed below are the most commonly used selective agents in established selective media formulations.

Click here for a list of the most commonly screened pathogens and selective agents.
 
 
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Lincomycin packaged and labeled in glass vial.
Lincomycin is a polar, water soluble, broad spectrum antibiotic first isolated from Streptomyces licolnensis by researchers at Upjohn...
Vancomycin packaged and labeled.
Vancomycin is a bactericidal glycopeptide antibiotic and has been used to treat infections...
Methicillin sodium packaged and labeled.
Methicillin sodium is a narrow spectrum β-lactam antibiotic in the penicillin family and is soluble in aqueous...
Novobiocin sodium packaged and labeled.
Novobiocin sodium is an aminocoumarin antibiotic that prevents cell division. Novobiocin sodium is freely soluble in aqueous...
Oleandomycin packaged and labeled in glass vial.
Oleandomycin is a 16-membered macrocyclic lactone, discovered in the 1950s, with broad spectrum antibacterial...
Oxolinic acid packaged and labeled.
Oxolinic acid is a synthetic quinolone antibiotic. Fluoroquinolone antibiotics target bacterial DNA gyrase, an enzyme...
Trimethoprim packaged and labeled.
Trimethoprim is a bactericidal dihydrofolate reductase inhibitor.TOKU-E offers two forms of trimethoprim: trimethoprim (T011) and trimethoprim lactate (T012). Trimethoprim...
Natamycin packaged and labeled.
Natamycin is a sparingly soluble (4.1 mg/mL) fungicidal polyene antifungal.
Trimethoprim lactate packaged and labeled.
Trimethoprim is a bactericidal dihydrofolate reductase inhibitor. Trimethoprim prevents bacteria from taking up folic...
Sulfadiazine packaged and labeled.
Sulfadiazine is a bacteriostatic sulfonamide antibiotic. Sulfadiazine interferes with the folic acid metabolism in bacteria by...
Vancomycin HCl, USP packaged and labeled.
Vancomycin HCl, USP is a bactericidal glycopeptide antibiotic. Vancomycin HCl is sparingly soluble in...
Sulfadiazine sodium packaged and labeled.
Sulfadiazine sodium is a bacteriostatic sulfonamide antibiotic. Sulfadiazine interferes with the folic acid metabolism in bacteria by...
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