Selective Agents

Several different types of antibiotics serve as selective agents in selective culture media to effectively isolate, or select for, a pathogenic microogranism from food, clinical, and environmental samples. Many times, these samples may contain a pathogenic microorganism among numerous types of relatively harmless bacteria and fungi. In order to effectively isolate the pathogenic organism, antibiotic selective agents are added to culture media to hinder growth of the harmless bacteria and fungi to ensure a non-competitive environment for the pathogenic organism.

An effective selective agent should not kill, or hinder the growth of the isolated pathogen. Theoretically, any antibiotic that doesn't target the selected pathogen but kills "background" growth of harmless microorganisms would be an ideal choice for use as a selective agent. The antimicrobials listed below are the most commonly used selective agents in established selective media formulations.

Click here for a list of the most commonly screened pathogens and selective agents.
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Ceftazidime pentahydrate packaged and labeled.
Ceftazidime Pentahydrate  is a broad-spectrum, third-generation, β-lactam cephalosporin.
Cephalothin sodium, USP packaged and labeled.
Cephalothin sodium, USP is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.  
Norfloxacin packaged and labeled.
Norfloxacin is a first generation synthetic fluoroquinolone antibiotic. Fluoroquinolone antibiotics target bacterial DNA...
Polymyxin B sulfate packaged and labeled.
Polymyxin B sulfate is a polypeptide antibiotic and is composed of polymyxins B1, B2, and B3 with fractions B1 and B2 comprising...
Cetrimide packaged and labeled.

Cetrimide is a bactericidal cationic surfactant used against Gram positive bacteria

Clindamycin hydrochloride packaged and labeled.

Clindamycin Hydrochloride is a broad-spectrum antibiotic and antiparasitic. 

Lincomycin HCl, USP packaged and labeled.
Lincomycin hydrochloride is a narrow-spectrum lincosamide effective for Gram-positive bacteria and protozoa.
Clindamycin phosphate packaged and labeled.
Clindamycin phosphate (clindamycin-2-phosphate) is a lincosamide antibiotic. TOKU-E offers two forms of clindamycin: clindamycin HCl (C035) and clindamycin phosphate (C036).  In aqueous solution, clindamycin...
Lincomycin HCl, EP packaged and labeled.

Lincomycin is a lincosamide effective for Gram-positive bacteria and protozoans. 

Colistin sodium methanesulfonate packaged and labeled.
Colistin sodium methanesulfonate is an inactive prodrug of Colistin.
Colistin sulfate, USP packaged and labeled.
Colistin sulfate, USP is a unique sparingly soluble cyclic polypeptide antibiotic known as polymyxin E.
Rifampicin packaged and labeled.
Rifampicin is a bacterial protein synthesis inhibiting antibiotic. Rifampicin targets prokaryotic DNA dependent RNA...
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