• Reveromycin B, EvoPure� packaged and labeled in glass vial.

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SKU: R029

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Description
Reveromycin B is an analogue of reveromycin A formed by rearrangement of the 6:6 spiroketal to a 5:6 spiroketal. Lacking much of the biological activity of reveromycin A, reveromycin B is a useful negative control in resolving the mode of action of this class.

Reveromycin B is soluble in ethanol, methanol, DMF and DMSO.  

    CAS Number

    144860-68-4

    Molecular Formula

    C36H52O11

    Molecular Weight

    660.8

    Storage Conditions

    -20°C

Specifications

    Appearance

    Tan Lyophilisate

References

    References

    Reveromycins, new inhibitors of eukaryotic cell growth. II. Biological activities. Takahashi H. et al. J. Antibiot. 1992, 45, 1414.

    Identification of Saccharomyces cerevisiae isoleucyl-tRNA synthetase as a target of the G1-specific inhibitor Reveromycin A. Miyamoto Y., et al. , J. Biol. Chem., 2002, 277, 28810.

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