• Resistoflavine packaged and labeled in glass vial.

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SKU: R025

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Description
Resistoflavine is a rare, boat-shaped, pentacyclic polyketide isolated from several species of Streptomyces, often co-produced with resistomycin. Resistoflavine exhibits weak antibacterial activity against Gram positive and Gram negative bacteria and exhibits potent cytotoxic activity against tumor cell lines in vitro. Resistoflavine inhibits growth, and nucleic acid and protein synthesis in Bacillus subtilis.

Resistoflavine is soluble in DMF and DMSO and is moderately soluble in methanol or ethanol.

    CAS Number

    29706-96-5

    Molecular Formula

    C22H16O7

    Molecular Weight

    392.4

    Storage Conditions

    -20°C

Specifications

    Appearance

    Brown solid

References

    References

    Zur konstitution des antibiotikums resistoflavin. Eckardt K. et al. , Tetrahedron 1970, 26, 5875.

    Effect of the antibiotics resistomycin and resistoflavin on growth, nucleic acid and protein synthesis in Bacillus subtilis. Haupt I. & Eckardt K., Z Allg Mikrobiol. 1972, 12, 575.

    Resistoflavine, cytotoxic compound from a marine actinomycete, Streptomyces chibaensis AUBN1/7. Gorajana A. et al. , Microbiol Res. 2007, 162, 322.

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