• Ramoplanin packaged and labeled in glass vial.

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SKU: R024

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Ramoplanin is a complex of three high molecular weight glycolipodepsipeptides, varying in the chain length and shape of the dieneone lipid side-chain. Ramoplanin was isolated in the early 1980s as the major metabolite of a strain of Actinoplanes with antiviral and antibiotic activity against drug resistant Gram positive isolates.

Ramoplanin is soluble in ethanol, methanol, DMF and DMSO.

    CAS Number


    Molecular Formula

    C119H154ClN21O40 (for A2)

    Molecular Weight

    2554.1 (for A2)

    Mechanism of Action

    Ramoplanin acts by inhibiting cell wall biosynthesis via a different mechanism from the vancomycin-related glycopeptides.

    Storage Conditions




    White solid



    A-16686, a new antibiotic from Actinoplanes. I. Fermentation, isolation and preliminary physico-chemical characteristics. Cavalleri B. et al. J. Antibiot. 1984, 37, 309.

    Bactericidal activity of ramoplanin against antibiotic-resistant enterococci. Johnson C.C. et al. Antimicrob. Agents Chemother. 1992, 36, 2342.

    Ramoplanin: a lipoglycodepsipeptide antibiotic. Farver D.K. et al. Ann. Pharmacother. 2005, 39, 863.

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