• Pseurotin A packaged and labeled in glass vial.

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SKU: P096

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Description
Pseurotin A is a fungal metabolite with an unusual hetero-spirocyclic ring system. It has potent neuritogenic activity in PC12 phaechromocytoma cells, a useful model for adrenergic neuronal differentiation. Pseurotin A also exhibits chitinase inhibition and acts synergistically with azole antifungal agents.

Pseurotin A is soluble in ethanol, methanol, DMF and DMSO.

    CAS Number

    58523-30-1

    Molecular Formula

    C22H25NO8

    Molecular Weight

    431.4

    Mechanism of Action

    Pseurotin A induces multipolar and branching neurites comparable to β-NGF, an endogenous neurotrophic factor.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    Novel neuritogenic activities of pseurotin A and penicillic acid. Komagata D. et al. J Antibiot. 1996, 49, 958.

    Synerazol, a new antifungal antibiotic. Ando O. et al. J Antibiot. 1991, 44, 382.

    Pseurotin, a new metabolite of Pseudeurotium ovalis Stolk having an unusual hetero-spirocyclic system. Bloch P. et al. Helv. Chim. Acta 1976, 59, 133.

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