• Pseudomonic acid packaged and labeled in glass vial.

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SKU: P095

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Description
Pseudomonic acid is a potent antibiotic produced by Pseudomonas fluorescens, reported by Fuller et al. in 1971. Pseudomonic acid has broad spectrum activity against Gram positive bacteria and was approved for topical human use in 1985.

Pseudomonic acid is soluble in ethanol, methanol, DMF and DMSO.

    CAS Number

    12650-69-0

    Molecular Formula

    C26H44O9

    Molecular Weight

    500.6

    Mechanism of Action

    Pseudomonic acid acts as a potent and selective inhibitor of isoleucyl-tRNA synthetase.

    Storage Conditions

    -20┬░C

Specifications

    Appearance

    White solid

References

    References

    Pseudomonic acid: an antibiotic produced by Pseudomonas fluorescens. Fuller A.T. et al. , Nature 1971, 234, 416.

    Antibacterial activity of mupirocin (pseudomonic acid), a new antibiotic for topical use. Sutherland R., Antimicrob Agents Chemother. 1985, 27, 495.

    Inhibition of isoleucyl-transfer ribonucleic acid synthetase in Echerichia coli by pseudomonic acid. Hughes J. & Mellows G., Biochem. J. 1978, 176, 305.

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