SKU: A160

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Description
Anacardic acid is a histone acetyltransferase (HAT) inhibitor that is derived from cashew shells. Anacardic acid is associated with anti-inflammatory, anti-tumor, molluscicidal, and anti-microbial activity. Anacardic acid is a common inhibitor of several clinically targeted enzymes such as NFκB kinase, histone acetyltransferase, lipoxygenase (LOX-1), xanthine oxidase, tyrosinase and ureases.

    CAS Number

    16611-84-0

    Molecular Formula

    C22H36O3

    Molecular Weight

    345.8

    Mechanism of Action

    Anacardic acid is a HAT (Histone Acetyltransferase) inhibitor.

    Storage Conditions

    -20┬░C

Applications

    Application

    Anacardic acid has been used for tooth abscesses, acnce, tuberculosis, and MRSA.

References

    References

    Satoh, M.,Takeuchi, N.,Fujita, T., et al. Synthesis of anacardic acids utilizing an annelation reaction of isoxazoles with ethyl acetoacetate. Chemical & Pharmaceutical Bulletin 46(10), 1501-1505 (1998).

    Balasubramanyam, K.,Swaminathan, V.,Ranganathan, A., et al. Small molecule modulators of histone acetyltransferase p300. The Journal of Biological Chemisty 278(21), 19134-19140 (2003).

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