• Pirarubicin

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SKU: P117

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Description
Pirarubicin is an anthracycline anticancer agent, an analogue of doxirubicin that is able to overcome some doxirubicin resistant cell lines.

TOKU-E offers  both pirarubicin (P116) and pirarubicin hydrochloride (P117). In aqueous solution, pirarubicin hydrochlloride is soluble in water. Pirarubicin is only slightly soluble in water.

    CAS Number

    72496-41-4

    Molecular Formula

    C32H37NO12

    Molecular Weight

    627.64

    Mechanism of Action

    Pirarubicin interacts with topoisomerase II, inhibiting the DNA polymerase complex and suppressing DNA replication.

References

    References

    Zhao, H., Yao, Y., Wang, Z., Lin, F., Sun, Y., & Chen, P. (2010). Therapeutic effect of Pirarubicin-Based chemotherapy for Osteosarcoma patients with lung Metastasis. Journal of Chemotherapy, 22(2), 119–124. doi:10.1179/joc.2010.22.2.119

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