• Pipacycline packaged and labeled in glass vial.

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SKU: P085

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Description
Pipacycline (mepicycline) is a semi-synthetic tetracycline formed by a Mannich condensation of formaldehyde and 4-hydroxyethylpiperazine with tetracycline. The introduction of the piperazine improves bioavailability, but Mannich bases are pro-drugs, converting back to the parent compound. Pipacycline is used commercially as a salt in combination with penicillin V for parenteral use (penimepicycline). The intrinsic in vitro activity and SARs for the amide region of the tetracycline molecule have not been investigated extensively. Pipacycline has not been extensively cited in the literature.

Pipacycline is soluble in ethanol, methanol, DMF or DMSO. Good water solubility.

    CAS Number

    1110-80-1

    Molecular Formula

    C29H38N4O9

    Molecular Weight

    586.6

    Storage Conditions

     -20°C

Specifications

    Appearance

    Yellow to orange solid

References

    References

    Antibiotic characteristics of mepicycline, a synthetic tetracycline derivative, and of penimepicycline, a new antibiotic compound. Gradnik G.G. Ital. Chemioter. 1962, 6-9:302-14

    Penimepicycline: studies on its chemical structure, physico-chemical properties, bioassay and chemical assay. Inahara H. et al. Jpn. J. Antibiot. 1969 22, 108.

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