Piericidin A is the major analogue of a family of pyridyl antibiotics isolated from selected Streptomyces species.
Piericidin A is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
CAS Number
2738-64-9
Molecular Formula
C25H37NO4
Molecular Weight
415.6
Mechanism of Action
Piericidin A is a specific, potent inhibitor of NADH-ubiquinone oxidoreductase (Complex I) that binds to ubiquinone binding site(s). Piericidin A inhibits both mitochondrial and bacterial NADH-ubiquinone oxidoreductases, binding close to NUOD-NUOB interface.
Storage Conditions
-20°C