SKU: P115

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Description
Pexiganan is an antimicrobial peptide (AMP) that is effective against a broad spectrum of bacteria including aerobic and anaerobic, gram-positive and gram-negative. Bacterial resistance to pexiganan is very unlikely to develop.

    CAS Number

    172820-23-4

    Molecular Formula

    C122H210N32O22

    Molecular Weight

    2477.2

    Mechanism of Action

    Pexiganan adopts a helix form in the cell membrane, causing pores in the membrane and leakage leading to cell death.

References

    References

    Gottler, L. M., & Ramamoorthy, A. (2009). Structure, membrane orientation, mechanism, and function of pexiganan — A highly potent antimicrobial peptide designed from magainin. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1788(8), 1680–1686. doi:10.1016/j.bbamem.2008.10.009

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