• Pentostatin packaged and labeled in glass vial.

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SKU: P076

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Description
Pentostatin is a potent antitumor antibiotic isolated from a Streptomyces species. Pentostatin is a potent inhibitor of adenine deaminase and has been used therapeutically as an antitumor agent.

Pentostatin is soluble in ethanol, methanol, DMF or DMSO. Good water solubility.

    CAS Number

    53910-25-1

    Molecular Formula

    C11H16N4O4

    Molecular Weight

    268.3

    Mechanism of Action

    Pentostatin is a potent inhibitor of adenine deaminase (ADA) and has been used therapeutically as an antitumor agent.

    Storage Conditions

    -20°C

References

    References

    A novel adenosine and ara-A deaminase inhibitor, (R)-3-(2-deoxy-b-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol. Woo P. W. K. et al. J. Het. Chem. 1974, 11, 641.

    Pentostatin: future directions. Klohs W. D. & Kraker A. J. Pharmacol Rev 1992, 44, 459.

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