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Description
Parvodicin is a family of glycopeptides with potent antibiotic activity, isolated from Actinomadura parvosata. Structurally the parvodicins share a common cyclic peptide core with ristocetin. The analogues within the complex vary in the fatty acid substitution on the aminosugar. Parvodicin complex is a precursor to the synthetic glycopepide, dalbavancin.

Parvodicin complex is soluble in ethanol, methanol, DMF or DMSO. Good water solubility.

    CAS Number

    187888-13-7

    Molecular Formula

    C83H88Cl2N8O29 (for C1)

    Molecular Weight

    1732.5 (for C1)

    Mechanism of Action

    Like other glycopeptides in this class, parvodicin complex inhibits cell wall formation by binding to D-alanine-D-alanine residues.

    Storage Conditions

    -20°C

Specifications

    Appearance

    Fawn to light tan solid

References

    References

    Parvodicin, a novel glycopeptide from a new species, Actinomadura parvosata: Discovery, taxonomy, activity and structure elucidation. Christensen S.B. et al. J. Antibiot. 1987, 40, 970.

    Dalbavancin: a novel antimicrobial. Chen A.Y. et al. Int. J. Clin. Pract. 2007, 61, 853.

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