• Oligomycin A, EvoPure� packaged and labeled in glass vial.

click on thumbnail to zoom
SKU: O013

  Click 'Bulk Order' for 10 or more
Price: make selection(s)
Oligomycin A is the dominant analogue of a class of macrocyclic lactones isolated from selected strains of Streptomyces sp. Oligomycin A exhibits a broad biological profile including antifungal, antitumor and nematocidal activities.

Oligomycin A is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

    CAS Number


    Molecular Formula


    Molecular Weight


    Mechanism of Action

    Oligomycin A is an inhibitor of mitochondrial F1F0-ATPase. It induces apoptosis in a variety of cell types, makes cells more susceptible to cell death, and also leads to a switch in the death mode from apoptosis to necrosis.

    Storage Conditions




    White Lyophilisate



    Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis. Miyoshi N., et al. , Proc. Natl Acad. Sci. U. S. A., 2006, 103, 1727.

    Mitochondria in eosinophils: functional role in apoptosis but not respiration. Peachman K. K., et al. , Proc. Natl Acad. Sci. U. S. A., 2001, 98, 1717.

    The BH3 domain is required for caspase-independent cell death induced by Bax and oligomycin. Fitch M. E., et al. , Cell Death Differ., 2000, 7, 338.

Other Items In This Category