• Norcantharidin

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SKU: N054

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Description
Norcantharidin is an antitumor drug that is a modified version of the natural product antitumor drug cantharidin. Norcantharidin is demethylated, which reduces its urinary system toxicity but not its antitumor efficacy. It has been found to induce apoptosis and act as an antineoplastic through the αvβ6-ERK signaling pathway.

    CAS Number

    29745-04-8

    Molecular Formula

    C8H8O4

    Molecular Weight

    168.15

References

    References

    Peng, C., Li, Z., Niu, Z., Niu, W., Xu, Z., Gao, H., … Niu, J. (2016). Norcantharidin suppresses colon cancer cell Epithelial-Mesenchymal transition by inhibiting the αvβ6-ERK-Ets1 signaling pathway. Scientific Reports, 6, 20500. doi:10.1038/srep20500

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