• Nogalamycin packaged and labeled in glass vial.

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SKU: N031

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Description
Nogalamycin is an unusual anthracycline produced by Streptomyces nogalater var. nogalater, reported by researchers at Upjohn in 1965. Nogalamycin contains two saccharides. The neutral monosaccharide attaches to the D ring, similar to the aminoglycoside moieties of the doxorubicin class, while the second, basic saccharide attaches to the phenolic group on the A ring in the ortho position to form a unique family of hexacyclic anthracyclines. Nogalamycin is potent antibacterial and antitumor agent.

Nogalamycin is soluble in ethanol, methanol, DMF or DMSO.

    CAS Number

    1404-15-5

    Molecular Formula

    C39H49NO16

    Molecular Weight

    787.8

    Mechanism of Action

    Nogalamycin interacts with DNA by intercalation.

    Storage Conditions

    -20°C

Specifications

    Appearance

    Red orange solid

References

    References

    Antibiotic nogalamycin and method of producing. Bhuyan B.K. et al. US Patent 3,183,157 1965.

    Fermentation, taxonomic and biological studies of nogalamycin. Bhuyan B.K. et al. Antimicrob. Agents Chemother. 1965, 5, 836.

    Structure of nogalamycin. Wiley P.F. J. Am. Chem. Soc. 1977, 99, 542.

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