• Moxidectin packaged and labeled in glass vial.

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SKU: M070

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Description
Moxidectin is a semi-synthetic milbemycin derived from nemadectin by selective oxidation followed by methyloximation. Moxidectin was patented in 1991 as an anthelmintic for internal parasite control. The presence of the methyloxime affords moxidectin a greater hydrophobicity and longer biological half-life compared to nemadectin.

Moxidectin is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

    CAS Number

    113507-06-5

    Molecular Formula

    C37H53NO8

    Molecular Weight

    639.8

    Mechanism of Action

    Moxidectin binds selectively to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite.

    Storage Conditions

    -20┬░C

Specifications

    Appearance

    White solid

References

    References

    Process for the preparation of 23-(C1-C6 alkyloxime)-LL-F28249 compounds. Maulding D. R & Kumar A. US Patent 4,988,824 (1991).

    Moxidectin: a review of chemistry, pharmacokinetics and use in horses. Cobb R. & Boeckh. A. Parasites and Vectors 2009, 2 (Suppl 2) S5.

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