• Moenomycin packaged and labeled in glass vial.

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SKU: M064

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Description
Moenomycin complex is a mixture of five major components, A, A12, C1, C3 and C4, isolated from several strains of Streptomyces in the 1960s. Moenomycins are high molecular weight phosphoglycolipids with potent antibiotic activity used in animal health.

Moenomycin is soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

    CAS Number

    11015-37-5

    Molecular Formula

    C69H107N4O35P (for A)

    Molecular Weight

    1583.6 (for A)

    Mechanism of Action

    Moenomycins are the only antibiotic known to selectively inhibit the transglycosylation step catalysed by penicillin-binding protein 1b.

    Storage Conditions

    -20┬░C

Specifications

    Appearance

    White to off-white solid

References

    References

    Moenomycin, a new antibiotic. II. Characterization and chemistry. Huber G. et al. Antimicrob. Agents Chemother. 1965, 5, 737.

    Membrane intermediates in the peptidoglycan metabolism of Escherichia coli: Possible roles of PBP 1b and PBP 3. Van Heijenoort Y. et al. J. Bacteriol. 1992, 174, 3549.

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