• Milbemycin D, EvoPure� packaged and labeled in glass vial.

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SKU: M061

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Description
Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin D is a minor member of a group of analogues containing a 25-isopropyl substituent. Milbemycin D is a highly selective and potent nematocide and insecticide.

Milbemycins are soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

    CAS Number

    77855-81-3

    Molecular Formula

    C33H48O7

    Molecular Weight

    556.7

    Mechanism of Action

    Like the closely related avermectin, milbemycins are thought to act by opening glutamate sensitive chloride channels.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    Milbemycins, a new family of macrolide antibiotics. Fermentation, isolation and physico-chemical properties of milbemycins D, E, F, G, and H. Takiguchi Y. et al. J Antibiot. 1983, 36, 502.

    Macrolide compounds, ivermectin and milbemycin D, stimulate chloride channels sensitive to GABAergic drugs in cultured chick spinal neurons. Yamazaki J. et al. Comp Biochem Physiol C. 1989, 93, 97.

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