• Meclocycline sulfosalicylate packaged and labeled in glass vial.

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SKU: M043

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Description
Meclocycline sulfosalicylate is a salt prepared from demeclocycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in solution with 2-hydroxy-3-carboxybenenesulphonic acid. Like all tetracyclines, meclocycline shows broad spectrum antibacterial and antiprotozoan activity. The unusual complex counter-ion is likely to add an antiseptic component to the use of the compound for skin infections.

Meclocycline sulfosalicylate is soluble in ethanol, methanol, DMF or DMSO. Good water solubility.

    CAS Number

    73816-42-9

    Molecular Formula

    C29H27ClN2O14S

    Molecular Weight

    695.1

    Mechanism of Action

    Like all tetracyclines acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.

    Storage Conditions

    -20┬░C

Specifications

    Appearance

    Yellow to orange solid

References

    References

    6-Methylenetetracyclines. I A new class of tetracycline antibiotics. Blackwood R.K. et al. J. Am. Chem. Soc. 1961, 83, 2773.

    6-Methylenetetracyclines. III. Preparation and Properties. Blackwood R.K. et al. J. Am. Chem. Soc. 1963, 85, 3943.

    Meclocycline sulfosalicylate. Topical antibiotic agent for the treatment of acne vulgaris. Knutson D. D. Cutis. 1981, 27, 203.

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