SKU: L042

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Description
Lydicamycin belongs to a novel structural class with highly selective antibiotic activity. Recent research has shown that lydicamycin and the related metabolites, TPU-0037A and TPU-0037C, are highly active against MRSA. Lydicamycin is also closely related to BN 4515N which was isolated from a strain of Microtetraspora as a neuritogenic agent.

Lydicamycin is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

    CAS Number

    133352-27-9

    Molecular Formula

    C47H74N4O10

    Molecular Weight

    855.1

    Storage Conditions

    -20┬░C

Specifications

    Appearance

    Colourless film

References

    References

    TPU-0037-A, B, C and D, novel lydicamycin congeners with anti-MRSA activity from Streptomyces platensis TP-A0598. Furumai T. et al. J. Antibiot. 2002, 55, 873.

    A new neuritogenetic compound BU-4514N produced by Microtetraspora sp.. Toda S. et al. J Antibiot. 1993, 46, 875.

    Lydicamycin, a new antibiotic of a novel skeletal type. I. Taxonomy, fermentation, isolation and biological activity. Hayakawa Y. et al. J Antibiot. 1991, 44, 282.

    Lydicamycin, a new antibiotic of a novel skeletal type. II. Physico-chemical properties and structure elucidation. Hayakawa Y. et al. J Antibiot. 1991, 44, 288.

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