• Lexithromycin packaged and labeled in glass vial.

click on thumbnail to zoom
SKU: L035

Size  
Quantity:
  Click 'Bulk Order' for 10 or more
Price: make selection(s)
Description
Lexithromycin is an early semi-synthetic erythromycin, prepared by reaction of the 9-keto moiety to methyl oxime. The structural change improves the pH stability profile and hydrophobicity of lexithromycin for better in vivo absorption. This same rationale was used to greater effect with roxithromycin and, as a result, lexithromycin was quickly superseded and has not been not extensively studied. Like all erythromycins, lexithromycin shows broad spectrum antibacterial activity.

Lexithromycin is soluble in ethanol, methanol, DMF or DMSO. Good water solubility.

    CAS Number

    53066-26-5

    Molecular Formula

    C38H70N2O13

    Molecular Weight

    763.0

    Mechanism of Action

    Like all erythromycins, lexithromycin acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    9-Substituted erythromycin A and B oximes. Von Esch A.M. 1972 US Patent 3,681,326.

Other Items In This Category