Gram-Negative Activity

Cell wall structure of Gram-negative bacteria and their susceptibility to antibiotics.

Gram-negative bacteria are a class of bacteria characterized by an outer layer of LPS (lipopolysaccharide) which does not allow retention of crystal violet stain during the Gram stain process. Gram-negative bacteria do synthesize peptidoglycan; however, the peptidolycan layer is sandwiched between an inner and outer membrane and is not directly exposed to the environment. Because of the outer LPS layer and hidden peptidoglycan layer, certain antibiotics are ineffective against Gram-negative bacteria. Well-known Gram-negative genera include Escherichia (includes E. coli), Pseudomonas, Neisseria (includes N. gonorrhoeae), Klebsiella, Proteus, Enterobacter, and Haemophilus.

The following antibiotics are effective against Gram-negative bacteria.

 
 
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Amikacin sulfate packaged and labeled.
Amikacin sulfate is broad spectrum aminoglycoside antibiotic derived from its counterpart kanamycin A...
Amoxicillin trihydrate packaged and labeled.
Amoxicillin is an extended spectrum β-lactam antibiotic and is similar in structure to ampicillin.  Resistance to Amoxicillin...
Ampicillin anhydrous packaged and labeled.
Ampicillin anhydrous is a member of the extended spectrum β-lactam family and similar in structure...
Ampicillin/sulbactam (2:1) packaged and labeled.
Ampicillin is a member of the extended spectrum β-lactam family and similar in structure to penicillin. Resistance to Ampicillin is...
Chloramphenicol palmitate packaged and labeled in glass vial.
Chloramphenicol palmitate is prepared by acylation of chloramphenicol with palmitic...
D-Cycloserine packaged and labeled.
D-cycloserine is an amino acid analog antibiotic. D-cycloserine acts as a competitive inhibitor of D-alanine...
Elaiophylin packaged and labeled in glass vial.
Elaiophylin is a highly characteristic metabolite produced by Streptomyces hygroscopicus. Elaiophylin inhibits testosterone 5-reductase...
Ertapenem sodium, EvoPure packaged and labeled.
Ertapenem sodium is a carbapenem, beta-lactam antibiotic with a broad antibacterial spectrum. Ertapenem sodium is...
Erythromycin Estolate packaged and labeled.
Erythromycin estolate is a macrolide antibiotic with a target spectrum similar to penicillin. TOKU-E offers three forms of erythromycin: erythromycin (E002), erythromycin...
Irgasan (Triclosan) packaged and labeled.
Irgasan (or triclosan) is a broad spectrum anti-fungal and antibiotic. Irgasan is slightly soluble in water and freely soluble...
Mitomycin C packaged and labeled.
Mitomycin C is a methylazirinopyrroloindoledione antineoplastic antibiotic isolated Streptomyces spp.
Nourseothricin (Streptothricin) Sulfate
Nourseothricin is an antibiotic in the Streptothricin class of antibiotics.
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