• Gamithromycin packaged and labeled in glass vial.

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SKU: G050

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Description
Gamithromycin is a semi-synthetic macrocyclic lactone belonging to the azalide class derived from erthyromycin, typified by azithromycin. The synthesis of gamithromycin involves a ring expansion using a Beckmann rearrangement to produce the 15-membered dibasic macrolide. Gamithromycin provides a broader spectrum of action, higher acid stability and improved bioavailability compared to older analogues of the erythromycin class and has been exclusively developed for animal health applications.

Gamithromycin is soluble in ethanol, methanol, DMF or DMSO.  

    CAS Number

    145435-72-9

    Molecular Formula

    C40H76N2O12

    Molecular Weight

    777

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    Antibacterial 9-deoxo-9a-alkyl-9a-aza-9a-homoerythromycin A derivatives and intermediates therefor. G.M. Bright US Patent 4,464,527 1985.

    Determination of the duration of antibacterial efficacy following administration of gamithromycin using a bovine Mannheimia haemolytica challenge model. Forbes A.B. et al. Antimicrob. Agents Chemother. 2011, 55, 831.

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