• Enniatin B, EvoPure� packaged and labeled in glass vial.

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SKU: E037

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Enniatins are a family of depsipeptide ionophores produced by several Fusarium species. Recently, the effects of the enniatins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus. Enniatin B is the most studied of four major analogues of the enniatin complex.

Enniatin B is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility. 

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    White powder



    Ionophore antibiotics produced by the fungus Fusarium orthoceras var. enniatum and other Fusaria. Gaumann E. et al. , Experientia 1947, 3, 202.

    "Sandwich" complexation in cyclopeptides and its implications in membrane processes. Ivanov V.T. Ann. N. Y. Acad. Sci. 1975, 264, 221.

    Interaction of cyclic peptides and depsipeptides with calmodulin. Mereish K.A. et al. , Pept. Res. 1990, 3, 233.

    Enniatin has a new function as an inhibitor of Pdr5p, one of the ABC transporters in Saccharomyces cerevisiae. Hiraga K. et al. , Biochem. Biophys. Res. Commun. 2005, 328, 1119.

    Enniatin exerts p53-dependent cytostatic and p53-independent cytotoxic activities against human cancer cells. Dornetshuber R. et al. , Chem. Res. Toxicol. 2007, 20, 465.

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