• Elaiophylin packaged and labeled in glass vial.

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SKU: E032

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Description
Elaiophylin is a highly characteristic metabolite produced by Streptomyces hygroscopicus. Elaiophylin inhibits testosterone 5-reductase. Elaiophylin is synergistic with its co-metabolite, rapamycin, as an antifungal. Elaiophylin also has anthelmintic and immunosuppressive activity and inhibits NO synthesis. Elaiophylin displays broad, albeit weak, biological activity against bacteria, nematodes, protozoa and mammalian tumor cells.

Elaiophylin is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

    CAS Number

    37318-06-2

    Molecular Formula

    C54H88O18

    Molecular Weight

    1025.3

    Storage Conditions

    >95% by HPLC

Specifications

    Appearance

    White Lyophilisate

References

    References

    Cation selective ion channels formed by macrodiolide antibiotic elaiophylin in lipid bilayer membranes. Grigoriev P.A. et al. Bioelectrochemistry 2001, 54, 11.

    Enhancement of the antifungal activity of rapamycin by the coproduced elaiophylin and nigericin. Fang A. et al. J Antibiot. 2000, 53,158.

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