• Dihydrocyclosporin A, EvoPure� packaged and labeled in glass vial.

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SKU: D053

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Description

Dihydrocyclosporin A is co-metabolite of Cyclosporin A. Dihydrocyclosporin A has no immunosuppressant activity and has found use as a control to determine the role of Cyclosporin A  in pharmacology, particularly in the treatment of parasitic infections. Dihydrocyclosporin A is soluble in ethanol, methanol, DMF and DMSO. 


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    CAS Number

    59865-15-5

    Molecular Formula

    C62H113N11O12

    Molecular Weight

    1204.6

    Storage Conditions

    -20°C

Applications

    Eukaryotic Cell Culture Applications

    Dihydrocyclosporin A is used as a control to determine the role of Cyclosporin A in pharmacology, particularly in parasitic infection.

Specifications

    Appearance

    White powder

References

    References

    Meier GP et al (1990) Isolation and identification of a novel human metabolite of cyclosporin A: dihydro-CsA M17. Drug Metab Dispos. 18:68

    Chappell LH et al (1987) Dosage, timing, and route of administration of cyclosporin A and nonimmunosuppressive derivatives of dihydrocyclosporin A and cyclosporin C against Schistosoma mansoni in vivo and in vitro. Antimicrob Agents Chemother. 31:1567

    Chappell LH et al (1989) Action of cyclosporin A on the tapeworms Hymenolepis microstoma, H. diminuta and Mesocestoides corti in vivo. Parasitology. 98:291

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