• Dihydrocyclosporin A, EvoPure� packaged and labeled in glass vial.

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SKU: D053

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Description
Dihydrocyclosporin A is a closely related co-metabolite of cyclosporin A. Dihydrocyclosporin A possesses no immunosuppressant activity and has found use as a control to determine the role of immunosuppression in the pharmacology of cyclosporin A, particularly in the treatment of parasitic infections.

Dihydrocyclosporin A is soluble in ethanol, methanol, DMF and DMSO. 

    CAS Number

    59865-15-5

    Molecular Formula

    C62H113N11O12

    Molecular Weight

    1204.6

    Storage Conditions

    -20°C

Specifications

    Appearance

    White powder

References

    References

    Isolation and identification of a novel human metabolite of cyclosporin A: dihydro-CsA M17. Meier G. P. et al. Drug Metab Dispos. 1990, 18, 68.

    Dosage, timing, and route of administration of cyclosporin A and nonimmunosuppressive derivatives of dihydrocyclosporin A and cyclosporin C against Schistosoma mansoni in vivo and in vitro. Chappell L. H. et al. Antimicrob Agents Chemother. 1987, 31, 1567. 

    Action of cyclosporin A on the tapeworms Hymenolepis microstoma, H. diminuta and Mesocestoides corti in vivo. Chappell L. H. et al. Parasitology. 1989, 98, 291.

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