• Demethoxyviridiol packaged and labeled in glass vial.

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SKU: D042

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Description
Demethoxyviridiol is a fungal metabolite belonging to the wortmannin and viridin classes. An inhibitor of phosphatidylinositol 3-kinase, demethoxyviridiol affects phospholipid signalling and proliferation of Swiss 3T3 cells.

Demethoxyviridiol is soluble in ethanol, methanol, DMF and DMSO. NOTE: stability problems if stored in methanol for protracted periods. 

    CAS Number

    56617-66-4

    Molecular Formula

    C19H16O5

    Molecular Weight

    324.3

    Storage Conditions

    -20┬░C

Specifications

    Appearance

    Tan solid

References

    References

    Inhibition of phospholipid signalling and proliferation of Swiss 3T3 cells by the wortmannin analogue demethoxyviridin. Cross M.J. et al. Biochim Biophys Acta. 1997, 1362, 29. 

    Effects of phosphatidylinositol-3-kinase inhibitors on degranulation and gene induction in allergically triggered mouse mast cells. Pendl G.G. et al. Int Arch Allergy Immunol. 1997, 112, 392. 

    Selective inhibition of p70 S6 kinase activation by phosphatidylinositol 3-kinase inhibitors. Petritsch C. et al. Eur J Biochem. 1995, 230, 431.

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