• Davercin packaged and labeled in glass vial.

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SKU: D035

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Description
Davercin (erythromycin A cyclic 11,12-carbonate) is a first generation semi-synthetic erythromycin. Davercin is prepared by coupling the 11- and 12-OH groups to form a cyclic carbonate. This simple modification improves the stability and hydrophobicity of the macrocyclic structure. Davercin shows comparable or better in vitro potency, low host toxicity and improved pharmacokinetics compared with erythromycin.

Davercin is soluble in ethanol, methanol, DMF and DMSO. 

    CAS Number

    55224-05-0

    Molecular Formula

    C38H65NO14

    Molecular Weight

    759.9

    Storage Conditions

    -20°C

Specifications

    Appearance

    White solid

References

    References

    Erythromycin derivatives and the process of preparation thereof. Murphy H.W. et al. U.S. Pat. 3,417,077, 1968

    L-aspartate of erythromycin A cyclic 11,12-carbonate, a new semisynthetic erythromycin derivative. Bojarska-Dahlig H. J. Antibiot. 1976, 29, 907.

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