• Dabrafenib

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SKU: D072

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Description
Dabrafenib is a selective inhibitor of BRAF, a proto-oncogene. It is primarily used for the treatment of late-stage melanoma.

    CAS Number

    1195765-45-7

    Molecular Formula

    C23H20F3N5O2S2

    Molecular Weight

    519.56

    Mechanism of Action

    Dabrafenib is a reversible and potent adenosine triphosphate-competitive inhibitor that selectively inhibits the BRAFV600E kinase.

References

    References

    Murali, R., M., & Long, G. (2012). Dabrafenib and its potential for the treatment of metastatic melanoma. DDDT Drug Design, Development and Therapy, 391. doi:10.2147/dddt.s38998

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