• Cytochalasin A, EvoPure� packaged and labeled in glass vial.

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SKU: C193

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Description
Cytochalasin A is one of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, giving rise to pronounced morphogenic activity in animals and plants. Despite the common mode of action, there is evidence that individual members of the class display diverse selectivity. Specifically, cytochalasin A is one of the few cytochalasins active against HIV-1 protease.

Cytochalasin A is soluble in ethanol, methanol, DMF and DMSO.

    CAS Number

    14110-64-6

    Molecular Formula

    C29H35NO5

    Molecular Weight

    477.6

    Mechanism of Action

    Cytochalasin A exhibits potent inhibition of actin filament function leading to cell death by apoptosis and displays a broad range of resultant cellular actions.

    Storage Conditions

    -20°C

Specifications

    Appearance

    White powder

References

    References

    The structures of cytochalasin A and B. Aldridge D. C. et al. J. Chem. Soc.1967, 1667. 

    L-696,474, a novel cytochalasin as an inhibitor of HIV-1 protease. III. Biological activity. Lingham R. B. et al. J. Antibiot. 1992, 45, 686.

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