Contamination Control

Contamination of cell cultures is a very common but serious issue in cell culture laboratories around the world. Contamination may arise from impurities in contaminated reagents, poor aseptic technique, and cross contamination by other cells used in the lab. Biological contaminants include bacteria and fungi (yeasts and molds) which thrive in nutrient rich cell culture media. The most common biological contaminant is the highly contagious and ubiquitous organism, Mycoplasma. Many studies have shown that a high percentage of cell cultures around the world are contaminated with Mycoplasma which is capable of altering cellular metabolism, protein synthesis, morphology, and most importantly, experimental data.

Contamination can be controlled or prevented by using the following antibiotics and antimycotics to eliminate or reduce the number of biological cell culture contaminants.

Contamination Control Categories

 
 
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Chloramphenicol succinate sodium packaged and labeled in glass vial.
Chloramphenicol succinate sodium is the salt prepared from chloramphenicol succinate using the free...
Kanamycin sulfate, USP packaged and labeled.
Kanamycin, USP is an aminoglycoside antibiotic often used to select for bacteria which have been successfully...
Caspofungin acetate packaged and labeled.
Caspofungin acetate is a sparingly soluble (0.367 mg/mL) lipopeptide antifungal which specifically targets the fungal...
Chloramphenicol packaged and labeled.
Chloramphenicol is a bacteriostatic antibiotic that inhibits bacterial protein synthesis. TOKU-E offers two forms...
Hygromycin B, EvoPure<sup>®</sup> (low endotoxin)
Hygromycin B is a unique aminoglycoside antibiotic derived from Streptomyces hygroscopicus...
Kanamycin acid sulfate packaged and labeled.
Kanamycin is an aminoglycoside antibiotic often used to select for bacteria which have been successfully...
Gentamicin sulfate, USP packaged and labeled.
Gentamicin sulfate is an aminoglycoside antibiotic composed of several different gentamicin components...
Nystatin packaged and labeled.
Nystatin is a sparingly soluble (0.360 mg/mL) fungicidal and fungistatic polyene antifungal.
Gentamicin sulfate, EP
Gentamicin sulfate, EP is an aminoglycoside antibiotic composed of several different gentamicin components...
Neomycin sulfate, EP packaged and labeled.
Neomycin sulfate, EP is a broad spectrum aminoglycoside antibiotic composed of a number of related neomycin...
Viridicatin packaged and labeled in glass vial.
Viridicatin is a fungal metabolite produced by several species of Penicillium and formed by the rearrangement of the...
De-Plasma™ II
To help scientists fight and control Mycoplasma contamination, TOKU-E has developed De-Plasma™ II...
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